5-ht5 Receptors

Supporting information

Serotonin 5-ht5 receptors are G-protein-coupled receptors that preferentially couple to Gs and promote cAMP formation. Two 5-ht5 receptor subtypes (5-ht5a and 5-ht5b) have been found in rodents, but a functional transcript of the 5-ht5a receptor has not been identified in humans.

To view external sources of pharmacological information for 5-ht5 Receptors, please click here: IUPHAR Receptor Code and BJP Guide

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Gene Species Gene Symbol Gene Accession No. Protein Accession No.
5-ht5A Human HTR5A NM_024012 P47898
Mouse Htr5a NM_008314 P30966
Rat Htr5b NM_013148 P35364
5-ht5B Human HTR5B XR_017010 Q9P2D3
Mouse Htr5b NM_010483 P31387
Rat Htr5b XM_341111 P35365

Literature for 5-ht5 Receptors

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
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GPCR Product Listing
5-HT Receptors Scientific Review

This review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in physiological and pharmacological processes. Compounds available from Tocris are listed.

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5-HT Receptors Scientific Review
Depression Life Science Poster

Written by Phil Skolnick, Piotr Popik and Ramon Trullas and updated in 2015, this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs. Compounds available from Tocris are listed.

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Depression Life Science Poster

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GPCR Product Listing

GPCR Product Listing

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5-HT Review

Written by N. Barnes & J. Neumaler

5-HT Receptors Scientific Review

Our 5-HT review summarizes the serotonin receptor subtypes and highlights their importance in mediating various physiological & pharmacological processes. Request copy or view PDF today.

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Antidepressants - Current and Future Targets

Written by P. Skolnich et al

Depression Life Science Poster

Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder. Request copy or view PDF today.

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