5-HT6 Receptors

More Information »Serotonin 5-HT6 receptors are located primarily in the striatum, olfactory tubercles, nucleus accumbens and hippocampus. Functions of 5-HT6 receptors include modulation of cholinergic and dopaminergic neurotransmission, and a role in spatial learning and memory.

5-HT6 Receptor Products

Agonists
Cat.No.
Product Name / Activity
2382 EMD 386088 hydrochloride
Potent 5-HT6 agonist
4209 EMDT oxalate
Selective 5-HT6 agonist
4337 ST 1936 oxalate
Selective, high affinity 5-HT6 agonist
5589 WAY 181187 oxalate
High affinity and selective 5-HT6 agonist
3904 WAY 208466 dihydrochloride
Selective 5-HT6 agonist
Antagonists
Cat.No.
Product Name / Activity
3326 BGC 20-761
High affinity 5-HT6 antagonist
4208 MS 245 oxalate
High affinity 5-HT6 antagonist
3285 NPS ALX Compound 4a dihydrochloride
Potent and selective 5-HT6 antagonist
4964 R 1485 dihydrochloride
Selective and high affinity 5-HT6 antagonist
2911 Ro 04-6790
Potent and selective 5-HT6 antagonist
1961 SB 258585 hydrochloride
Potent, selective 5-HT6 antagonist
3368 SB 271046 hydrochloride
Selective, orally active 5-HT6 antagonist
3189 SB 399885 hydrochloride
Potent and selective 5-HT6 antagonist
3688 SGS 518 oxalate
Selective 5-HT6 antagonist
Other
Cat.No.
Product Name / Activity
0590 Metergoline
Has moderate affinity for 5-HT6 and high affinity for 5-HT7. Also 5-HT1/5-HT2 antagonist
0558 2-Methyl-5-hydroxytryptamine hydrochloride
5-HT3 agonist/potent 5-HT6 ligand
0997 Mianserin hydrochloride
Has moderate affinity for 5-HT6. Also 5-HT2 antagonist
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