Checkpoint Control Kinases

More Information »Checkpoint control kinases is a term used to describe a group of enzymes that regulate progression of a cell through the cell cycle. Catastrophic genetic damage can occur if cells progress to the next phase of the cell cycle before the previous phase is properly completed.

Checkpoint Control Kinase Products

Inhibitors
Cat.No.
Product Name / Activity
5198 AZ 20
Potent and selective ATR kinase inhibitor; antitumor
3994 AZ 3146
Potent and selective Mps1 inhibitor
5199 AZD 7762 hydrochloride
Potent and selective ATP-competitive inhibitor of Chk1 and Chk2
4968 CCT 241533 dihydrochloride
Potent Chk2 inhibitor
3271 Compound 401
Selective DNA-PK and mTOR inhibitor
2088 DMNB
DNA-PK inhibitor
4840 KU 0060648
Dual DNA-PK and PI 3-K inhibitor
3544 KU 55933
Potent and selective ATM kinase inhibitor
4176 KU 60019
Potent ATM kinase inhibitor
3190 Mirin
MRN-ATM pathway inhibitor
5562 Mps BAY 2a
Potent and selective Mps1 kinase inhibitor
5142 Mps1-IN-1 dihydrochloride
Selective Mps1 kinase inhibitor
3034 NSC 109555 ditosylate
Selective Chk2 inhibitor
2828 NU 7026
Selective DNA-PK inhibitor
3712 NU 7441
Potent and selective DNA-PK inhibitor
3785 PD 166285 dihydrochloride
Wee1 inhibitor; also inhibits Src, FGFR and PDGFRβ
2694 PD 407824
Selective inhibitor of Chk1 and Wee1
4277 PF 477736
Selective Chk1 inhibitor
3140 PHA 767491 hydrochloride
Dual cdc7/cdk9 inhibitor. Also inhibits MK2
2930 PI 103 hydrochloride
Inhibitor of DNA-PK, mTOR and PI 3-kinase
2560 SB 218078
Inhibitor of checkpoint kinase 1 (Chk1)
4750 TC Mps1 12
Potent and selective Mps1 kinase inhibitor; orally active
3038 TCS 2312
Potent Chk1 inhibitor
Other
Cat.No.
Product Name / Activity
4502 DIM
Activates Chk2; induces G2/M cell cycle arrest
4763 Pyridostatin pentahydrochloride
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
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Kinase Inhibitor Toolbox

80 Kinase inhibitors
pre-dissolved in DMSO

Kinase Inhibitor Toolbox

Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.

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Kinases Product Listing

Kinases Product Listing

Our Kinase listing highlights over 400 products for kinase research. Request copy or view PDF today.

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