Mitosis

More Information »Mitosis is a highly complex and regulated sequence of events that occurs exclusively in eukaryotic cells and produces two identical daughter cells from a single parent cell. It is split into five phases; prophase, prometaphase, metaphase, anaphase and telophase.

Mitosis Products

 
Cat.No.
Product Name / Activity
5747 Apcin
Cdc20 inhibitor; inhibits Cdc20-substrate interaction
5736 Aphidicolin
DNA polymerase α, δ and ε inhibitor; antimitotic
5454 BRD 9876
ATP non-competitive kinesin Eg5 inhibitor
5399 BTB1
Selective and ATP-competitive Kif18A inhibitor
5687 Centrinone
High affinity and selective PLK4 inhibitor
5690 Centrinone B
High affinity and selective PLK4 inhibitor
1364 Colchicine
Inhibitor of tubulin
1495 Combretastatin A4
Tubulin polymerization inhibitor. Antitumor, antiangiogenic and antimetastatic
5130 CTCE 9908
CXCR4 antagonist; induces mitotic catastrophe in ovarian cancer cells
3116 Cyclapolin 9
Selective, ATP-competitive PLK1 inhibitor
1643 D-64131
Tubulin polymerization inhibitor. Antitumor in vivo
5261 Dimethylenastron
Inhibitor of mitotic motor kinesin Eg5; antimitotic
3375 Dolastatin 10 trifluoroacetate
Tubulin polymerization inhibitor
1774 Dynamin inhibitory peptide
Dynamin inhibitor
1775 Dynamin inhibitory peptide, myristoylated
Cell-permeable dynamin inhibitor
1776 Dynamin inhibitory peptide, myristoylated (control)
Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)
2897 Dynasore
Non-competitive dynamin inhibitor
3502 Epothilone B
Microtubule stabilization agent; promotes G2-M cell cycle arrest
2226 Flutax 1
Fluorescent taxol derivative
2977 GW 843682X
Selective inhibitor of PLK1 and PLK3
3728 Indibulin
Microtubule destabilizer
3551 INH1
Hec1 inhibitor; causes arrest of mitosis
3982 Mdivi 1
Selective inhibitor of dynamin related GTPase; attentuates mitochondrial division
3213 Methylene Blue
Inhibitor of tau aggregation
4224 MitMAB
Dynamin inhibitor
5683 MMAE
Potent dolastatin 10 analog; antitumor
1305 Monastrol
Selective inhibitor of mitotic kinesin Eg5
1228 Nocodazole
Microtubule inhibitor
1697 Noscapine hydrochloride
Tubulin inhibitor; induces apoptosis
4225 OctMAB
Dynamin inhibitor
4292 SBE 13 hydrochloride
Potent and selective PLK1 inhibitor
5403 TAK 960 hydrochloride
Potent and selective PLK1 inhibitor
4506 TAME hydrochloride
Ubiquitin ligase APC/C inhibitor; promotes Cdc20 autoubiquitination
1097 Taxol
Promotes assembly and inhibits disassembly of microtubules
4459 TC-S 7005
Potent and selective PLK2 inhibitor
2191 S-Trityl-L-cysteine
Potent, selective inhibitor of mitotic kinesin Eg5
1256 Vinblastine sulfate
Disrupts microtubules
1257 Vincristine sulfate
Disrupts microtubules
3401 Vinorelbine ditartrate
Selective mitotic microtubule antagonist
1232 Wortmannin
Potent inhibitor of PLK1. Also inhibitor of PI 3-kinase
3101 XRP44X
Microtubule depolymerization agent. Also Ras-Net pathway inhibitor
2458 ZM 447439
Inhibits Aurora kinase B
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