LXR-like Receptors

More Information »Liver X receptors (LXRs) and farnesoid X receptors (FXRs) are members of the steroid analog-activated nuclear receptor subfamily, which form heterodimers with members of the retinoid X receptor family. There are two closely related isoforms of each of these enzymes; α and β.

LXR-like Receptor Products

Agonists
Cat.No.
Product Name / Activity
2563 Fexaramine
Potent, selective farnesoid X receptor (FXR) agonist
2474 GW 3965 hydrochloride
Orally active liver X receptor (LXR) agonist
2473 GW 4064
Selective farnesoid X receptor (FXR) agonist
3907 27-Hydroxycholesterol
LXR agonist; also ER partial agonist
2373 T 0901317
Potent liver X receptor (LXR) agonist; also CAR inverse agonist
5951 WAY 252623
Potent LXR agonist
Antagonists
Cat.No.
Product Name / Activity
5656 DY 268
Potent FXR antagonist
5694 GSK 2033
Potent LXR antagonist
5854 SR 9238
Potent and selective LXR inverse agonist
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