Toll-like Receptors

More Information »Toll-like receptors (TLRs) are single transmembrane cell-surface receptors, which have a key role in the innate immune system. TLRs generally exist as homodimers (heterodimers have been reported) and are found on immune cells; macrophages, B lymphocytes and mast cells.

Toll-like Receptor Products

Agonists
Cat.No.
Product Name / Activity
5414 CU-T12-9
Potent TLR1/2 agonist
4809 DSR 6434
Potent TLR7 agonist
3700 Imiquimod
Toll-like receptor 7 (TLR7) agonist
4637 Pam2CSK4
TLR2/6 agonist; induces TNF-α production
4638 Pam2CSK4 Biotin
Biotinylated Pam2CSK4 (Cat. No. 4637)
4633 Pam3CSK4
TLR1/2 agonist; induces cytokine production
4636 Pam3CSK4 Biotin
Biotinylated Pam3CSK4 (Cat. No. 4633)
4287 Poly(I:C)
TLR3 agonist
4536 Resiquimod
Toll-like receptor 7 (TLR7) agonist
5928 RS 09
TLR4 peptide agonist; acts as an adjuvant in vivo
2719 RWJ 21757
Toll-like receptor 7 (TLR7) agonist
5445 SM 324405
Potent TLR7 agonist
Inhibitors
Cat.No.
Product Name / Activity
5373 C34
TLR4 inhibitor
4884 CU CPT 22
Selective TLR1/2 inhibitor
4883 CU CPT 4a
Selective TLR3 inhibitor
5648 Hydroxychloroquine sulfate
TLR9 inhibitor; also Autophagy inhibitor
Other
Cat.No.
Product Name / Activity
3270 GIT 27
Interferes with TLR4, TLR2/6 signaling
Related Categories

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Immunology Guide

Immunology Product Listing

Our Immunology listing highlights over 190 products for immunology research. Request copy or view PDF today.

divider line

Toll-like Receptor Pathway

Toll-like Receptor Signaling Pathway

Toll-like receptors are important in the inflammatory and adaptive and innate immune responses against threatening microbes. View pathway or download PDF today.

divider line

ASCB 2016

Win a $1,000 travel grant

ASCB travel Grant

Bio-Techne is offering 10 travel grants of $1,000 for ASCB 2016.