Toll-like Receptors

More Information »Toll-like receptors (TLRs) are single transmembrane cell-surface receptors, which have a key role in the innate immune system. TLRs generally exist as homodimers (heterodimers have been reported) and are found on immune cells; macrophages, B lymphocytes and mast cells.

Toll-like Receptor Products

Product Name / Activity
5414 CU-T12-9
Potent TLR1/2 agonist
4809 DSR 6434
Potent TLR7 agonist
6011 FSL 1
TLR2/6 agonist (also a putative TLR10 ligand)
3700 Imiquimod
Toll-like receptor 7 (TLR7) agonist
4637 Pam2CSK4
TLR2/6 agonist; induces TNF-α production
4638 Pam2CSK4 Biotin
Biotinylated Pam2CSK4 (Cat. No. 4637)
4633 Pam3CSK4
TLR1/2 agonist; induces cytokine production
4636 Pam3CSK4 Biotin
Biotinylated Pam3CSK4 (Cat. No. 4633)
4287 Poly(I:C)
TLR3 agonist
4536 Resiquimod
Toll-like receptor 7 (TLR7) agonist
5928 RS 09
TLR4 peptide agonist; acts as an adjuvant in vivo
2719 RWJ 21757
Toll-like receptor 7 (TLR7) agonist
5445 SM 324405
Potent TLR7 agonist
Product Name / Activity
5373 C34
TLR4 inhibitor
4884 CU CPT 22
Selective TLR1/2 inhibitor
4883 CU CPT 4a
Selective TLR3 inhibitor
5648 Hydroxychloroquine sulfate
TLR9 inhibitor; also Autophagy inhibitor
Product Name / Activity
3270 GIT 27
Interferes with TLR4, TLR2/6 signaling
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