- Type I cytokine receptors: include the IL-2 receptor, growth hormone receptor and erythropoietin receptor, are linked to JAK tyrosine kinases.
- Type II cytokine receptors: include interferon receptors are also linked to JAK tyrosine kinases.
- Immunoglobulin superfamily receptors: also classed as cell adhesion molecules, and family members include the IL-1 and IL-18 receptors.
- The tumor necrosis factor family: also known as death receptors as they have a role in the extrinsic apoptotic pathway.
- Chemokine receptors: G-protein-coupled receptors that have a role in innate and adaptive immunity.
- TGF-β receptors: serine/threonine kinase-coupled receptors with a role in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death.
|Gene||Species||Gene Symbol||Gene Accession No.||Protein Accession No.|
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Literature for Cytokine Receptors
A collection of over 750 products for cancer research, the guide includes research tools for the study of:
- Cancer Metabolism
- Epigenetics in Cancer
- Receptor Signaling
- Cell Cycle and DNA Damage Repair
- Invasion and Metastasis
A collection of over 190 products for immunology research, the guide includes research tools for the study of:
- Chemokine and Cytokine Signaling
- Complement System
- Immune Cell Signaling
Written by Grant D. Nicol and Michael R. Vasko, this poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described. Compounds available from Tocris are listed.Request copy | Download PDF | View all posters