TGF-β Receptors

More Information »The transforming growth factor-β family of polypeptides (TGF-β1-3) are involved in the regulation of cellular processes, including division, differentiation, motility, adhesion and death. TGF-β signals by binding the type II receptor (TGF-βRII) which activates the type I receptor (TGF-βRI).

TGF-β Receptor Products

Inhibitors
Cat.No.
Product Name / Activity
2939 A 83-01
Selective inhibitor of TGF-βRI, ALK4 and ALK7
2902 D 4476
TGF-βRI inhibitor. Also inhibits CK1
3264 GW 788388
Potent and selective inhibitor of TGF-βRI
2718 LY 364947
Selective inhibitor of TGF-βRI
5288 R 268712
Potent and selective inhibitor of TGF-βRI
3742 RepSox
Potent and selective inhibitor of TGF-βRI
1614 SB 431542
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
3263 SB 505124
Selective inhibitor of TGF-βRI, ALK4 and ALK7
3211 SB 525334
Selective inhibitor of TGF-βRI
3269 SD 208
Potent ATP-competitive TGF-βRI inhibitor
Other
Cat.No.
Product Name / Activity
5679 N-Acetylpuromycin
Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
5068 ITD 1
Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs
5291 SIS3
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
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