More Information »Dihydrofolate reductase (DHFR) is a member of the reductase family of enzymes that is ubiquitously expressed in all organisms. It catalyzes tetrahydrofolate regeneration by reduction of dihydrofolate, using NADPH as a cofactor. DHFR has a key role in cell growth and proliferation.
Dihydrofolate Reductase Products
Product Name / Activity
|Dihydrofolate reductase inhibitor|
|High affinity dihydrofolate reductase inhibitor; also inhibits thymidylate synthase, GARFT and AICART|
|DHFR inhibitor; also potent inhibitor of multidrug and toxin extrusion (MATE) transporters and STAT3 inhibitor|