More Information »Spleen tyrosine kinase (Syk) is a non-receptor cytoplasmic enzyme that is primarily expressed in cells of hematopoietic lineage. Syk contains two adjacent SH2 domains that bind to immunoreceptor tyrosine-based activation motifs (ITAMs) to activate the enzyme.
Syk Kinase Products
Product Name / Activity
|2471||ER 27319 maleate|
|Selective Syk kinase inhibitor|
|5592||LCB 03-0110 dihydrochloride|
|Potent Syk kinase inhibitor; also inhibits BTK, c-Src and DDR2|
|Selective inhibitor of Syk and Src|
|Syk kinase inhibitor; inhibits Aβ production|
|Potent Syk kinase inhibitor; also inhibits assembly of NLRP3 inflammasomes|
|Syk and p56lck kinase inhibitor|
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