mTOR

More Information »mTOR (mechanistic Target Of Rapamycin, mammalian Target Of Rapamycin) plays a key role in coordinating cell signaling pathways. mTOR is a large (>280kD), multidomain protein with a kinase domain and a FKBP12 binding domain.

mTOR Products

Inhibitors
Cat.No.
Product Name / Activity
5615 AZD 3147
Potent and selective dual mTORC1 and 2 inhibitor; orally bioavailable
3271 Compound 401
Selective mTOR and DNA-PK inhibitor
4702 ETP 45658
mTOR inhibitor; also inhibits PI 3-K and DNA-PK
3725 KU 0063794
Selective mTOR inhibitor
4079 Niclosamide
STAT3 inhibitor; also inhibits mTORC1 signaling
4820 PF 04691502
Dual PI 3-K/mTOR inhibitor
4823 PF 05212384
Potent and selective dual PI 3-kinase/mTOR inhibitor
2930 PI 103 hydrochloride
Inhibitor of mTOR, PI 3-kinase and DNA-PK
3894 PP 121
Dual kinase inhibitor; inhibits PI 3K family kinases
4257 PP 242
Dual mTORC1/mTORC2 inhibitor
1292 Rapamycin
mTOR inhibitor; immunosuppressant
5264 Temsirolimus
mTOR inhibitor; antitumor
4247 Torin 1
Potent and selective mTOR inhibitor
4248 Torin 2
Potent and selective mTOR inhibitor
4282 WYE 687 dihydrochloride
Potent and selective mTOR inhibitor
4893 XL 388
Potent and selective mTOR inhibitor; antitumor
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