Gonadotropin-Releasing Hormone Receptors

Supporting information

Gonadotropin-releasing hormone (GnRH) receptors are a group of Gq/11-protein-coupled receptors that are divided into two subtypes; GnRH and GnRH2. GnRH receptors are predominantly expressed by pituitary gonadotrophs and are found at lower concentrations in the ovary, breast, placenta, prostate, heart and kidneys.

GnRH regulates the biosynthesis and secretion of follicle-stimulating hormone (FSH) and luteinising hormone (LH) and the human gene encoding the GnRH receptor is localized on chromosome 4q21.2. GnRH2 is silenced in humans but in other mammals it stimulates sexual behavior and has neuromodulatory activity.

To view external sources of pharmacological information for Gonadotropin-Releasing Hormone Receptors, please click here: IUPHAR Receptor Code and BJP Guide

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Gene Species Gene Symbol Gene Accession No. Protein Accession No.
GnRH Human GNRHR NM_000406 P30968
Mouse Gnrhr NM_010323 Q01776
Rat Gnrhr NM_031038 P30969
GnRH2 Human GNRHR2 NR_002328 Q96P88

Literature for Gonadotropin-Releasing Hormone Receptors

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Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

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Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

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