Hydroxycarboxylic Acid Receptors
Hydroxycarboxylic acid (HCA) receptors, previously known as nicotinic acid receptors, are Gi/Go protein-coupled receptors for which hydroxycarboxylic acids are endogenous ligands. Three HCA receptors are known to exist: HCA1 (GPR81), HCA2 (GPR109A) and HCA3 (GPR109B).
GPR109B receptors originated from a gene duplication of GPR109A and have >95% homology. All subtypes are widely expressed throughout adipose tissue and are found at lower levels in macrophages, neutrophils, Langerhans cells and in the spleen. The human genes encoding these receptors are located on chromosome 12 (12q24.3).View all products for Hydroxycarboxylic Acid Receptors »
|Gene||Species||Gene Symbol||Gene Accession No.||Protein Accession No.|
Literature for Hydroxycarboxylic Acid Receptors
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Secretin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Find multiple products by catalog number
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.