Smoothened Receptor Antagonists

 
Cat.No.
Product Name / Activity
1623 Cyclopamine
Inhibitor of Hedgehog (Hh) signaling; Smo antagonist
5554 IHR 1
Potent Smo antagonist
5561 IHR-Cy3
Potent fluorescent Smo antagonist
5981 Itraconazole
SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)
4717 Jervine
Inhibitor of Hedgehog (Hh) signaling; binds directly to Smo
4917 M 25
Potent Smoothened (Smo) receptor antagonist
4585 MRT 10
Smoothened (Smo) antagonist
5262 PF 5274857 hydrochloride
High affinity and selective Smoothened (Smo) receptor antagonist
1974 SANT-1
Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity
3617 SANT-2
Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity

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