Cannabinoid transporters, often referred to as anandamide membrane transporters (AMTs), uptake endocannabinoids and limit their activity at CB1, CB2 and GPR55 receptors. Cannabinoid transporters facilitate endocannabinoid breakdown by internalizing the molecule and allowing access to fatty acid amide hydrolase (FAAH).
As endocannabinoids are widely distributed, it has been suggested that AMTs are also found in many different tissues, although this is as yet unverified. The cannabinoid transporter is thought to play a vital role in the endocannabinoid system, but currently little is known about it and the gene encoding this protein is uncharacterized.View all products for Cannabinoid Transporters »
Literature for Cannabinoid Transporters
A collection of over 250 products for pain research, the guide includes research tools for the study of:
- Ion Channels
- G-Protein-Coupled Receptors
- Intracellular Signaling
Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.Request copy | Download PDF | View all reviews
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