VEGFR

More Information »Vascular endothelial growth factor is a signaling protein involved in the regulation of angiogenesis and vasculogenesis. VEGF binds to and activates a receptor tyrosine kinase, VEGFR, through transphosphorylation. Three VEGFR isoforms have been identified in humans.

VEGFR Products

Inhibitors
Cat.No.
Product Name / Activity
5318 AEE 788
Potent VEGFR and EGFR inhibitor
2617 AG 879
VEGFR-2 inhibitor
4274 AP 24534
Potent multi-kinase and pan-Bcr-Abl inhibitor
4350 Axitinib
Potent VEGFR-1, -2 and -3 inhibitor
4471 DMH4
Selective VEGFR-2 inhibitor
3882 (E)-FeCP-oxindole
Selective VEGFR-2 inhibitor
3883 (Z)-FeCP-oxindole
Selective VEGFR-2 inhibitor
2542 Ki 8751
Potent, selective VEGFR-2 inhibitor
1459 SU 4312
Potent inhibitor of VEGFR tyrosine kinase
3300 SU 5402
Potent VEGFR and FGFR inhibitor
3037 SU 5416
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
3335 SU 6668
VEGFR, PDGFR and FGFR inhibitor
3768 Sunitinib malate
Potent VEGFR, PDGFRβ and KIT inhibitor
3909 Toceranib
Potent PDGFR and VEGFR inhibitor
5680 Vatalanib succinate
Potent VEGFR inhibitor; also aromatase inhibitor
5422 XL 184
Potent VEGFR inhibitor; also inhibits other RTKs
2499 ZM 306416 hydrochloride
Inhibitor of VEGF receptor tyrosine kinase
2475 ZM 323881 hydrochloride
Potent, selective inhibitor of VEGFR-2
Other
Cat.No.
Product Name / Activity
4931 EG 00229
Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1
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