Src Kinases

More Information »Src kinases consist of eight non-receptor tyrosine kinases (Src, Fyn, Yes, Lck, Lyn, Hck, Fgr and Blk) that interact with the intracellular domains of growth factor/cytokine receptors, GPCRs and integrins. Members of the Src kinase family have a very similar domain structure.

Src Kinase Products

Inhibitors
Cat.No.
Product Name / Activity
3914 A 419259 trihydrochloride
Inhibitor of Src family kinases
3963 AZM 475271
Src tyrosine kinase inhibitor
4361 Bosutinib
Dual Src-Abl inhibitor; antiproliferative
1936 Damnacanthal
Potent, selective p56lck inhibitor; also LIMK1/2 inhibitor
1629 Herbimycin A
Src family kinase inhibitor. Also Hsp90 inhibitor
4660 KB SRC 4
Potent and selective c-Src inhibitor
1331 Lavendustin A
EGFR, p60c-src inhibitor
5592 LCB 03-0110 dihydrochloride
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
2265 Lyn peptide inhibitor
Inhibits Lyn activation via hematopoietin βc receptor; cell-permeable
2877 MNS
Selective inhibitor of Src and Syk
3063 1-Naphthyl PP1
Src family kinase inhibitor; also inhibits c-Abl
3785 PD 166285 dihydrochloride
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
4965 PD 180970
p210Bcr/Abl kinase inhibitor; also inhibits c-Src and KIT
1554 Piceatannol
p56lck and Syk kinase inhibitor
1397 PP 1
Potent, selective Src family kinase inhibitor
1407 PP 2
Potent, selective Src family kinase inhibitor
2794 PP 3
Negative control for PP 2 (Cat. No. 1407)
1923 pp60 c-src (521-533) (phosphorylated)
Inhibits tyrosine kinase activity of pp60c-src and pp60v-src
3642 Src I1
Dual site Src kinase inhibitor
3567 TC-S 7003
Potent Lck inhibitor
5413 WH-4-023
Potent and selective Lck and Src inhibitor; also inhibits SIK
Activators
Cat.No.
Product Name / Activity
4582 MLR 1023
Selective allosteric activator of Lyn kinase
Ligands
Cat.No.
Product Name / Activity
1930 N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide
Phosphopeptide ligand for src SH2 domain
1927 N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu
Phosphopeptide ligand for src SH2 domain
1935 Caffeic acid-pYEEIE
Phosphopeptide ligand for src SH2 domain
Other
Cat.No.
Product Name / Activity
4763 Pyridostatin pentahydrochloride
Stabilizes G-quadruplexes; targets the proto-oncogene SRC
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