PDGFR

More Information »Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation.

PDGFR Products

Inhibitors
Cat.No.
Product Name / Activity
5013 AC 710
Potent and selective PDGFR family inhibitor
0493 AG 18
EGFR/PDGFR-kinase inhibitor
4274 AP 24534
Potent multi-kinase and pan-Bcr-Abl inhibitor
1222 DMPQ dihydrochloride
Potent, selective inhibitor of PDGFRβ
5906 Imatinib mesylate
PDGFR inhibitor; also inhibits v-Abl tyrosine kinase and c-kit
5260 KG 5
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor; antiangiogenic
3785 PD 166285 dihydrochloride
PDGFRβ, FGFR and Src inhibitor; also inhibits Wee1
3304 SU 16f
Potent and selective PDGFRβ inhibitor
3335 SU 6668
PDGFR, VEGFR and FGFR inhibitor
3768 Sunitinib malate
Potent VEGFR, PDGFRβ and KIT inhibitor
3909 Toceranib
Potent PDGFR and VEGFR inhibitor
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