p53 Activators

 
Cat.No.
Product Name / Activity
3503 HLI 373
Hdm2 inhibitor; activates p53-dependent transcription
2185 NSC 146109 hydrochloride
Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription
5065 NSC 319726
Reactivator of mutant p53
2936 NSC 66811
MDM2 inhibitor. Disrupts MDM2-p53 interaction
3984 Nutlin-3
MDM2 antagonist; inhibits MDM2-p53 interaction
2443 RITA
p53-MDM2 interaction inhibitor; antitumor
3929 SJ 172550
MDMX inhibitor. Disrupts MDMX-p53 interaction
5332 SP 141
High affinity MDM2 inhibitor
3365 Tenovin-1
Activates p53 transcriptional activity
3356 WR 1065
p53 activator. Also ROS scavenger

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Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

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Cell Cycle Life Science Poster

Cell Cycle & DNA Damage Repair Life Science Poster

Our Cell Cycle & DNA Damage Repair poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death. Request copy or view PDF today.

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p53 Life Science Poster

Written by Christopher J. Brown et al

p53 Life Science Poster

A summary of the main strategies for the reactivation of p53, including small molecules and peptides, which act to stabilize p53 to rescue wild-type activity. Request copy today.

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p53 Signaling Pathway

p53 Signaling Pathway

Signals through the p53 pathway are integral in the control of the cellular response different types of stress. View pathway or download PDF today.

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