More Information »Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of α- and β-tubulin polymers. Each microtubule is polarized; at one end α-subunits are exposed (-) and at the other, β-subunits are exposed (+).

Microtubule Products

Product Name / Activity
4138 ABT 751
Inhibitor of microtubule polymerization; antimitotic and antitumor
6043 AMBMP hydrochloride
Tubulin polymerization inhibitor; also Wnt canonical signaling activator
2186 CMPD-1
Tubulin polymerization inhibitor; also selective inhibitor of p38α-mediated MK2a phosphorylation
1364 Colchicine
Inhibitor of tubulin
1495 Combretastatin A4
Tubulin polymerization inhibitor. Antitumor, antiangiogenic and antimetastatic
1643 D-64131
Tubulin polymerization inhibitor. Antitumor in vivo
4056 Docetaxel
Microtubule stabilizer
3375 Dolastatin 10 trifluoroacetate
Tubulin polymerization inhibitor
3502 Epothilone B
Microtubule stabilization agent; promotes tubulin polymerization
2226 Flutax 1
Fluorescent taxol derivative
5075 Harmine
Potent and selective Dyrk1A inhibitor; inhibits tau phosphorylation
3728 Indibulin
Microtubule destabilizer
4997 INDY
Dyrk1A/B inhibitor; inhibits abberant tau phosphorylation
3213 Methylene Blue
Inhibitor of tau aggregation
5683 MMAE
Potent dolastatin 10 analog; antitumor
5231 MPC 6827 hydrochloride
Inhibitor of microtubule polymerization; antimitotic and antitumor
1228 Nocodazole
Microtubule inhibitor
1697 Noscapine hydrochloride
Tubulin inhibitor; induces apoptosis
1097 Taxol
Promotes assembly and inhibits disassembly of microtubules
4286 UA 62784
Inhibits microtubule polymerization
1256 Vinblastine sulfate
Disrupts microtubules
1257 Vincristine sulfate
Disrupts microtubules
3401 Vinorelbine ditartrate
Selective mitotic microtubule antagonist
3101 XRP44X
Microtubule depolymerization agent. Also Ras-Net pathway inhibitor
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