Life Science Posters

A range of posters authored by leading experts

Authored by leading experts in the field, and summarizing key areas of research, the following range of life science posters provide a colorful and informative source of information. In addition, we have a series of cancer posters adapted from the Cancer Product Guide, Edition 3. We invite you to request your copy today.

Addiction

Mechanisms of Addiction

Prof David Nutt, Imperial College London

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Request copy | Download PDF
Addiction Life Science Poster

Alzheimer's

Alzheimer's Disease: Neurobiology and Drug Targets

Alan M. Palmer, MS Therapeutics Ltd.

Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.

Request copy | Download PDF
Alzheimer's Life Science Poster

Angiogenesis

Tumor- and Stromal Cell-Derived Pathways as Targets for Anti-Angiogenic Therapy

Napoleone Ferrara and Yongping Crawford, Genentech

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.

Request copy
Angiogenesis Life Science Poster

Asthma

New Therapies, Challenges, and Breakthroughs in Asthma

Peter J. Barnes, Imperial College London

Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. This poster highlights key pathways and new therapies used to treat the condition, including those currently in clinical development.

Request copy
Asthma Life Science Poster

Autophagy

Autophagy: Mechanisms and Function

Patricia Boya, CSIC
Patrice Codogno, University Paris-Descartes

Autophagy is a cellular process used by cells for degradation and recycling. Written by Patricia Boya and Patrice Codogno, this poster summarizes the molecular machinery, physiology and pathology of autophagy. Compounds available from Tocris are listed.

Request copy | Download PDF
Autophagy Life Science Poster

Cancer Metabolism

Taken from the Cancer Guide Edition 3

Adapted from the 2015 Cancer Product Guide, Edition 3, this poster summarizes the main targets for cancer metabolism researchers. Genetic changes and epigenetic modifications in cancer cells alter the regulation of cellular metabolic pathways. These distinct metabolic circuits could provide viable cancer therapeutic targets.

Request copy | Download PDF
Cancer Metabolism Life Science Poster

Cardiovascular

Regulation of Vascular Reactivity by G-protein-coupled Receptors

Janet J. Maguire and Anthony P. Davenport, University of Cambridge

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

Since going to print, the authors of this poster have notified us of an improvement they wish to make: under the Gq/11 heading, M2 should be amended to M3.

Request copy
Cardiovascular Life Science Poster

Cell Cycle & DNA Damage Repair

Taken from the Cancer Guide Edition 3

In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. Adapted from the 2015 Cancer Product Guide, Edition 3, this poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.

Request copy | Download PDF
Cell Cycle & DNA Damage Repair Life Science Poster

Depression

Antidepressants - Current and Future Targets

Phil Skolnick, National Institutes of Health
Piotr Popik, Jagiellonian University
Ramon Trullas, Consejo Superior de Investigaciones Científicas (CSIC)

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

Request copy | Download PDF
Depression Life Science Poster

Epigenetics in Cancer

Taken from the Cancer Guide Edition 3

Adapted from the 2015 Cancer Product Guide Edition 3, this poster summarizes the main epigenetic targets in cancer. The dysregulation of epigenetic modifications has been shown to result in oncogenesis and cancer progression. Unlike genetic mutations, epigenetic alterations are considered to be reversible and thus make promising therapeutic targets.

Request copy | Download PDF
Epigenetics in Cancer Life Science Poster

Gut Hormones

Gut Hormones and the Regulation of Appetite

Victoria J. Taylor, Preeti H. Jethwa, Caroline J. Small and Stephen R. Bloom, Imperial College London

The gastrointestinal tract is the largest endocrine gland in the human body, secreting hormones that affect digestion, appetite and energy expenditure. Neuropeptide modulators and gut hormones that influence appetite are reviewed in this poster.

Request copy
Gut Hormones Life Science Poster

Huntington's Disease

Huntington's Disease: Pathophysiology and Clinical Prospects

Annalena Wieland and Nicholas Allen, University of Cardiff

Huntington's disease (HD) is a monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the MSN intracellular signaling pathways implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.

Request copy | Download PDF
Huntington's Disease Life Science Poster

Learning & Memory

Neurotransmitters of Synaptic Plasticity, Learning and Memory in the Perirhinal Cortex

E. Clea Warburton and Zafar I. Bashir, University of Bristol

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.

Request copy | Download PDF
Learning & Memory Life Science Poster

Multiple Sclerosis

Multiple Sclerosis: from Neurobiology to Therapy

Alastair Wilkins and Richard Ibitoye

Multiple sclerosis (MS) is an autoimmune disease that is characterized by focal demyelination and axon degeneration in the central nervous system. This poster summarizes the neurobiology and current therapies of MS.

Request copy | Download PDF
Multiple Sclerosis Life Science Poster

p53

Strategies to Reactivate the p53 Tumor Suppressor Response

Christopher J. Brown, Chit F. Cheok, David P. Lane and Chandra S. Verma, A*STAR

p53 is a key transcriptional regulator that is found to be frequently mutated and inactivated in tumors. This poster summarizes the main strategies that may be utilized to reactivate p53 including several small molecules and peptides which act to stabilize p53 and rescue wild-type activity.

Request copy
p53 Life Science Poster

Pain

Modulation of Peripheral Sensitisation

Grant D. Nicol and Michael R. Vasko, Indiana University

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.

Request copy | Download PDF
Pain Life Science Poster

Parkinson's

Parkinson's Disease: Neurobiology and Therapeutic Strategies

Anthony H.V. Schapira, University College London

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.

Request copy | Download PDF
Parkinson's Life Science Poster

Programmed Cell Death

Apoptosis, Necroptosis and Cell Survival

Bram van Raam, Universiteit Gent
Guy Salvesen, Sanford-Burnham Medical Research Institute

There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.

Request copy | Download PDF
Programmed Cell Death Life Science Poster

Schizophrenia

Schizophrenia: Emerging Targets and Therapeutic Strategies

Jeffery Lieberman, Jacob Ballons, Nancy Bivens, Zachary Freyberg, Ragy Girgis,Caline Karam, Jose Lizardi-Ortiz, Sander Markx and Jonathan Javitch,Columbia University College of Physicians and Surgeons

Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster highlights the targets and pathways representing the most promising strategies to pursue for novel drug development.

Request copy
Schizophrenia Life Science Poster

Quick Order

Find multiple products by catalog number

divider line

Sign up to our E-Alerts

Win an iPad Air 2 or Mini 4

e-alerts

To receive the latest product news relevant to your interests, sign up to our e-alerts or update your details, and you will automatically be entered into the draw to win an iPad Air 2 or Mini 4 of your choice.

divider line

Bio-Techne Events

Neuroscience 2016

Neuroscience 2016

November 12 - 16, 2016

San Diego, CA, USA

Booth: 3217