Ro 04-5595 hydrochloride
Cat. No. 2005
Chemical Name: 1-[2-(4-Chlorophenyl)ethyl]-1,2,3,4
Biological ActivitySelective antagonist for NR2B-containing NMDA receptors (Ki = 31 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Mutel et al (1998) In vitro binding properties in rat brain of [3H] Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits. J.Neurochem. 70 214.
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Citations are publications that use Tocris products. Selected citations for Ro 04-5595 hydrochloride include:
Voyer (2017) Repeated ventral midbrain neurotensin injections sensitize to amphetamine-induced locomotion and ERK activation: A role for NMDA receptors Neuropharmacology 112 150. PMID: 27267684.
Do you know of a great paper that uses Ro 04-5595 hydrochloride from Tocris? If so please let us know.
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