c-JUN peptide

Cat. No. 1989

c-JUN peptide Ile-Leu-Lys-Gln-Ser-Met-Thr-Leu-Asn-Leu-Ala-Asp-Pro-Val-Gly-Ser-Leu-Lys-Pro-His-Leu-Arg-Ala-Lys-Asn

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Biological Activity

Peptide comprising residues 33 - 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells.

Technical Data

Soluble to 1 mg/ml in water
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Holzberg et al (2003) Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN d domain induces apoptosis and affects a distinct set of interleukin-1 induced inflammatory genes. J.Biol.Chem. 278 40213. PMID: 12832416.

If you know of a relevant reference for c-JUN peptide please let us know.

Citations are publications that use Tocris products. Selected citations for c-JUN peptide include:

Moreau et al (2015) Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. J Urol 6 8045. PMID: 26289944.

Do you know of a great paper that uses c-JUN peptide from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: c-JUN peptide, supplier, JNK, c-Jun, interaction, inhibitors, inhibits, Peptide, N-Terminal, Kinases, Transcription, Factors, Mitogen-Activated, protein, Tocris Bioscience, JNK/c-Jun Inhibitor products

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