Cat. No. 1975
Biological ActivityPotent competitive vanilloid TRPV1 (VR1) receptor antagonist (IC50 = 10 nM). Inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons, and guinea pig bladder and trachea contractions in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Appendino et al (2003) Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists. Br.J.Pharmacol. 139 1417. PMID: 12922928.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses 6-Iodonordihydrocapsaicin from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: 6-Iodonordihydrocapsaicin, supplier, Potent, competitive, vanilloids, receptors, antagonists, VR1, TRPV, Channels, Transient, Receptor, Potential, Tocris Bioscience, TRPV Antagonist products
Find multiple products by catalog number
New Products in this Area
Potent TRPV1 antagonistPF 05105679
Selective TRPM8 blockerM 084 hydrochloride
TRPC4/5 channel blocker; antidepressant and anxiolyticA 425619
Potent TRPV1 antagonistRN 9893 hydrochloride
Potent and selective TRPV4 antagonist
November 12 - 16, 2016
San Diego, CA, USA