Cat. No. 1956
Alternative Name: Ubenimex
Chemical Name: N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-
Biological ActivityAminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Scornik and Botbol (2001) Bestatin as an experimental tool in mammals. Curr.Drug Metab. 2 67. PMID: 11465152.
Imamura and Kimura (2000) Effect of ubenimex (Bestatin) on the cell growth and phenotype of HL-60 and HL-60R cell lines: up- and down-regulation of CD13/aminopeptidase N. Leuk.Lymphoma 37 663. PMID: 11042531.
Umezawa et al (1976) Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. J.Antibiot. 29 97. PMID: 931798.
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Citations are publications that use Tocris products.
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Keywords: Bestatin, supplier, Aminopeptidase, inhibitors, inhibits, enkephalin, metabolism, leukotrienes, eicosanoids, A4, hydrolase, Proteases, Proteinases, Tocris Bioscience, Aminopeptidase Inhibitor products