GR 79236

Cat. No. 1957

GR 79236 C15H21N5O5 [124555-18-6]

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Chemical Name: N-[(1S,2S)-2-Hydroxycyclopentyl]adenosine

Biological Activity

Adenosine A1 receptor agonist (Ki = 3.1 nM). Anticonvulsive in mice following systemic administration in vivo.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Technical Data

M.Wt:
351.36
Formula:
C15H21N5O5
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
124555-18-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Knutsen et al (1999) N-Substituted adenosines as novel neuroprotective A1 agonists with diminished hypotensive effects. J.Med.Chem. 42 3463. PMID: 10479279.

Merkel et al (1995) Cardiovascular and antilipolytic effects of the adenosine agonist GR 79236. Pharmacology 51 224. PMID: 8577816.

Gurden et al (1993) Functional characterization of three adenosine receptor types. Br.J.Pharmacol. 109 693. PMID: 8358566.

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Keywords: GR 79236, supplier, A1, agonists, Receptors, adenosines, GR79236, GlaxoSmithKline, GSK, Tocris Bioscience, A1 Receptor Agonist products

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