Cat. No. 1957
Chemical Name: N-[(1S,2S)-2-Hydroxycyclopentyl]ade
Biological ActivityAdenosine A1 receptor agonist (Ki = 3.1 nM). Anticonvulsive in mice following systemic administration in vivo.
Licensing InformationSold for research purposes under agreement from GlaxoSmithKline
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Knutsen et al (1999) N-Substituted adenosines as novel neuroprotective A1 agonists with diminished hypotensive effects. J.Med.Chem. 42 3463. PMID: 10479279.
Merkel et al (1995) Cardiovascular and antilipolytic effects of the adenosine agonist GR 79236. Pharmacology 51 224. PMID: 8577816.
Gurden et al (1993) Functional characterization of three adenosine receptor types. Br.J.Pharmacol. 109 693. PMID: 8358566.
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Citations are publications that use Tocris products.
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Keywords: GR 79236, supplier, A1, agonists, Receptors, adenosines, GR79236, GlaxoSmithKline, GSK, Tocris Bioscience, Adenosine A1 Receptor Agonist products