Cat. No. 1953
Chemical Name: [(3-Methoxyphenyl)methylene]hydrazo
Biological ActivityNegative allosteric modulator of the metabotropic glutamate receptor mGlu5; displays reversible non-competitive inhibition of mGlu5-mediated responses (IC50 = 3 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
O'Brien et al (2003) A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5 Mol.Pharmacol. 64 731. PMID: 12920211.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses DMeOB from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: DMeOB, supplier, Negative, allosteric, modulators, mGlu5, mGluR5, Group, I, Receptors, Glutamate, Metabotropic, nams, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Modulator products
Find multiple products by catalog number
New Products in this Area
Selective mGlu2 receptor positive allosteric modulator
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.