Cat. No. 1953
Chemical Name: [(3-Methoxyphenyl)methylene]hydrazo
Biological ActivityNegative allosteric modulator of the metabotropic glutamate receptor mGlu5; displays reversible non-competitive inhibition of mGlu5-mediated responses (IC50 = 3 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
O'Brien et al (2003) A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5 Mol.Pharmacol. 64 731. PMID: 12920211.
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Citations are publications that use Tocris products.
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Keywords: DMeOB, supplier, Negative, allosteric, modulators, mGlu5, mGluR5, Group, I, Receptors, Glutamate, Metabotropic, nams, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Modulator products