Cat. No. 1953
Chemical Name: [(3-Methoxyphenyl)methylene]hydrazo
Biological ActivityNegative allosteric modulator of the metabotropic glutamate receptor mGlu5; displays reversible non-competitive inhibition of mGlu5-mediated responses (IC50 = 3 μM).
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
O'Brien et al (2003) A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5 Mol.Pharmacol. 64 731. PMID: 12920211.
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Keywords: DMeOB, supplier, Negative, allosteric, modulators, mGlu5, mGluR5, Group, I, Receptors, Glutamate, Metabotropic, nams, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Modulator products
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