Cat. No. 2831
Chemical Name: 1-(3-Chlorophenyl)-2-[(1,1-dimethyl
Biological ActivityNon-selective inhibitor of dopamine and noradrenalin transporters (Ki values are 1.4, 2.8 and 45 μM for NET, DAT and SERT transporters respectively). Also inhibits neuronal nicotinic acetylcholine receptors. Displays antidepressant activity and augments nicotine self-administration at low doses in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Dwoskin et al (2006) Review of the pharmacology and clinical profile of bupropion, antidepressant and tobacco use cessation agent. CNS Drug Rev. 12 178. PMID: 17227286.
Torres et al (2003) Plasma membrane monoamine transporters: structure regulation and function. Nat.Rev.Neurosci. 4 13. PMID: 12511858.
Slemmer et al (2000) Bupropion is a nicotinic antagonist. J.Pharmacol.Exp.Ther. 295 321. PMID: 10991997.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Bupropion hydrochloride from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Bupropion hydrochloride, supplier, Non-Selective, inhibitors, inhibits, dopamine, noradrenaline, transporters, NET, Adrenergic, Monoamine, Neurotransmitter, DAT, Dopamine, reuptake, Tocris Bioscience, Dopamine Transporter Inhibitor products
Find multiple products by catalog number
New Products in this Area
High affinity and selective presynaptic choline transporter (CHT) inhibitor
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.