Cat. No. 1944
Alternative Name: SCH 29851
Chemical Name: 4-(8-Chloro-5,6-dihydro-11H-benzo[5
Biological ActivityPeripheral histamine H1 receptor antagonist (Ki = 35 nM); devoid of central effects. Orally active antiallergic agent.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Kreutner et al (1987) Antiallergic activity of loratidine, a non-sedating antihistamine. Allergy 42 57. PMID: 2436504.
Ahn and Barnett (1986) Selective displacement of [3H]mepyramine from peripheral vs. central nervous system receptors by loratadine, a non-sedating antihistamine. Eur.J.Pharmacol. 127 153. PMID: 2875889.
Barnett et al (1984) Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine. Agents Actions 14 590. PMID: 6236679.
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Citations are publications that use Tocris products.
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Keywords: Loratidine, supplier, Peripheral, H1, antagonists, anti-allergic, agent, Receptors, Histamine, histaminergic, SCH29851, Tocris Bioscience, Histamine H1 Receptor Antagonist products