Neuropeptide AF (human)

Cat. No. 1928

Neuropeptide AF (human) Ala-Gly-Glu-Gly-Leu-Asn-Ser-Gln-Phe-Trp-Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2

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Alternative Names: NPAF, Neuropeptide NPAF (human FMRFamide-related)

Biological Activity

Endogenous antiopioid peptide, implicated in pain modulation and endocrine functions. May also regulate metabolism via stimulation of β-adrenoceptor expression in adipocytes.

Technical Data

M.Wt:
1978.19
Formula:
C90H132N26O25
Sequence:
AGEGLNSQFWSLAAPQRF

(Modifications: Phe-18 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
192387-38-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Lefrere et al (2002) Neuropeptide AF and FF modulation of adipocyte metabolism. J.Biol.Chem. 277 39169. PMID: 12149260.

Elshourbagy et al (2000) Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J.Biol.Chem. 275 25965. PMID: 10851242.

Vilim et al (1999) Gene for pain modulatory neuropeptide FF: induction in spinal cord by noxious stimuli. Mol.Pharmacol. 55 804. PMID: 10220558.

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Keywords: Neuropeptide AF (human), supplier, Implicated, pain, modulation, Anti-opioids, neuropeptides, FF, AF, NPFF, Receptors, Tocris Bioscience, Neuropeptide FF/AF Receptor products

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