Neuromedin U (rat)

Cat. No. 1917

Neuromedin U (rat) Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-Gly-Gly-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2

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Biological Activity

Endogenous peptide regulating blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function. Also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo.

Technical Data

M.Wt:
2643
Formula:
C124H180N34O31
Sequence:
YKVNEYQGPVAPSGGFFLFRPRN

(Modifications: Asn-23 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
117505-80-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Mondal et al (2003) Neuromedin U acts in the cental nervous system to inhibit gastric acid secretion via CRH system. Am.J.Physiol.Gastrointest.Liver Physiol. 284 G963. PMID: 12584108.

Szekeres et al (2000) Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. J.Biol.Chem. 275 20247. PMID: 10811630.

Minamino et al (1985) Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 130 1078. PMID: 3841690.

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Keywords: Neuromedin U (rat), supplier, NMU, Receptors, agonists, NeuromedinU, (rat), Tocris Bioscience, Neuromedin U Receptor Agonist products

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