Cat. No. 1913
Biological ActivityBombesin receptor antagonist; inhibits bombesin-induced amylase release in guinea pig pancreas (IC50 = 4 mM). Centrally active in vivo.
(Modifications: X = Glp, Phe-12 = D-Phe, Gly-14 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Merali et al (1988) (D-Phe12) Bombesin and substance P analogues function as central bombesin receptor antagonists. Synapse 2 282. PMID: 2463692.
Moody et al (1988) Localization of receptors for bombesin-like peptides in the rat brain. Ann.N.Y.Acad.Sci. 547 114. PMID: 2853589.
Heinz-Erian et al (1987) [D-Phe12]Bombesin analogues: a new class of bombesin receptor antagonists. Am.J.Physiol. 252 G439. PMID: 2435173.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses [D-Phe12]-Bombesin from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: [D-Phe12]-Bombesin, supplier, Bombesin, receptor, antagonists, GRP-Preferring, Receptors, BB1-3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Tocris Bioscience, Bombesin Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
Non-peptide apelin receptor agonistBML 111
FPR2 (lipoxin A4 receptor) agonistAmylin (rat)
Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptorsCalcitonin (human)
Endogenous calcitonin receptor agonist; inhibits bone resorptionSpexin
Potent GAL2/3 agonist; exhibits anxiolytic effects in vivoMM 54
Potent apelin receptor antagonist
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.