Neuromedin B (porcine)

Cat. No. 1908

Neuromedin B (porcine) Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2

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Biological Activity

Mammalian bombesin-like peptide and endogenous ligand for the neuromedin B receptor (IC50 = 2 nM); first isolated from pig spinal cord. Regulates endocrine and exocrine secretion, smooth muscle contraction, blood pressure, feeding and cell growth.

Technical Data

M.Wt:
1132.3
Formula:
C52H73N15O12S
Sequence:
GNLWATGHFM

(Modifications: Met-10 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
87096-84-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Ohki-Hamazaki et al (2000) Neuromedin B. Prog.Neurobiol. 62 297. PMID: 10840151.

Sainz et al (1998) Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor. J.Biol.Chem. 273 15927. PMID: 9632639.

Minamino et al (1983) Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 114 541. PMID: 6882442.

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