Cat. No. 1898
Biological ActivityEndogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia.
(Modifications: Cys-15 = C-terminal OH, Disulfide Bridge between 4 - 2, 7 - 5)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Beltowski (2001) Guanylin and related peptides. J.Physiol.Pharmacol. 52 351. PMID: 11596856.
Nokihara et al (1997) Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer. Regul.Pept. 70 111. PMID: 9272623.
Currie et al (1992) Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc.Natl.Acad.Sci.U.S.A. 89 947. PMID: 1346555.
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Keywords: Guanylin (human), supplier, Endogenous, activators, intestinal, guanylyl, cyclase, sGC, Guanylyl, cyclases, Tocris Bioscience