MAPK Cascade Inhibitor Tocriset™

Cat. No. 1878

Contents of Tocriset:
Cat.No.
Product Name / Activity
1110Genistein
epidermal growth factor receptor (EGFR) kinase inhibitor
1144U0126
potent and selective inhibitor of MAP2K
1202SB 203580
selective inhibitor of p38 MAPK
1213PD 98059
inhibitor of MAPKK / MEK
1321ZM 336372
potent, selective c-Raf inhibitor

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Biological Activity

Contains the listed products which can be used to inhibit various kinases in the MAPK signal transduction pathway. The products are supplied either as a solid (U0126) or pre-dissolved in DMSO at a stock concentration of 10 mM in 0.5 ml.

Technical Data

Tocrisets contain 3-5 ligands supplied as lyophilized solids or pre-dissolved in DMSO at a specified concentration. Lyophilized solids have been freeze-dried (approximately 0.5-2 mg per vial) so that addition of 0.5 or 1 ml of solvent produces a stock concentration of 10 or 5 mM respectively.

Please see individual product listings for specific technical data and certificate of analysis.

Product Data Sheet / Safety Data Sheet

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References

Please see individual product listings for specific references.

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