MAPK Cascade Inhibitor Tocriset™
Cat. No. 1878
Contents of Tocriset:
Product Name / Activity
|epidermal growth factor receptor (EGFR) kinase inhibitor|
|potent and selective inhibitor of MAP2K|
|selective inhibitor of p38 MAPK|
|inhibitor of MAPKK / MEK|
|potent, selective c-Raf inhibitor|
Biological ActivityContains the listed products which can be used to inhibit various kinases in the MAPK signal transduction pathway. The products are supplied either as a solid (U0126) or pre-dissolved in DMSO at a stock concentration of 10 mM in 0.5 ml.
Tocrisets contain 3-5 ligands supplied as lyophilized solids or pre-dissolved in DMSO at a specified concentration. Lyophilized solids have been freeze-dried (approximately 0.5-2 mg per vial) so that addition of 0.5 or 1 ml of solvent produces a stock concentration of 10 or 5 mM respectively.
Please see individual product listings for specific technical data and certificate of analysis.
Product Data Sheet / Safety Data Sheet
ReferencesPlease see individual product listings for specific references.
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