pp60 c-src (521-533) (phosphorylated)

Cat. No. 1923

pp60 c-src (521-533) (phosphorylated) Thr-Ser-Thr-Glu-Pro-Gln-pTyr-Gln-Pro-Gly-Glu-Asn-Leu

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Biological Activity

Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.

Technical Data

M.Wt:
1543.5
Formula:
C62H95N16O28P
Sequence:
TSTEPQYQPGENL

(Modifications: Tyr-7 = pTyr)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
149299-77-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Harder et al (1994) Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. Biochem.J. 298 395. PMID: 8135747.

Roussel et al (1991) Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxy terminus of pp60c-src. Proc.Natl.Acad.Sci.U.S.A. 88 10696. PMID: 1720546.

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Keywords: pp60 c-src (521-533) (phosphorylated), supplier, inhibitors, inhibits, tyrosine, kinase, activity, pp60c-src, pp60v-src, Src, Kinases, Tocris Bioscience, Src Kinase Inhibitor products

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