Cat. No. 1860
Chemical Name: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl
Biological Activity5-HT1 and 5-HT2C receptor partial agonist (Ki values are 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively). Reduces 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Gommans et al (1997) Discriminative stimulus properties of eltoprazine. Life Sci. 61 11. PMID: 9200664.
Schipper et al (1990) Neurochemical profile of eltoprazine. Drug Metabol.Drug Interact. 8 85. PMID: 1982626.
Miczek et al (1989) Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor subtypes. Psychopharmacol.Bull. 25 399. PMID: 2483273.
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Keywords: Eltoprazine hydrochloride, supplier, 5-HT2C, receptor, partial, agonists, 5-HT1, Serotonin, Receptors, Tocris Bioscience, 5-HT1B Receptor Agonist products