Exo1

Cat. No. 1850

Exo1 C15H12FNO3 [461681-88-9]

Price and Availability

For Exo1 pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 2-[(4-Fluorobenzoyl)amino]-benzoic acid methyl ester

Biological Activity

Reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC50 ~ 20 mM). Has similar, but not identical, action to brefeldin A (Cat. No. 1231).

Technical Data

M.Wt:
273.26
Formula:
C15H12FNO3
Solubility:
Soluble to 25 mM in ethanol with gentle warming and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
461681-88-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Feng et al (2003) Exo1: A new chemical inhibitor of the exocytic pathway. Proc.Natl.Acad.Sci.U.S.A. 100 6469. PMID: 12738886.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Exo1 from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Exo1, supplier, inhibitors, inhibits, Golgi-ER, traffic, blocks, exocytosis, Golgi, ADP-ribosylation, factor, ARF1, GTPase, Tocris Bioscience, Translocation, Exocytosis & Endocytosis products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

New Products in this Area

SAG 21k

Hedgehog signaling activator; brain penetrant and orally bioavailable

G10

Activator of STING-dependent signaling

3',3'-cGAMP sodium salt

STING agonist

2',3'-cGAMP sodium salt

Endogenous high affinity STING agonist

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.