Cat. No. 1847
Alternative Name: (-)-Eticlopride
Chemical Name: 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2
Biological ActivitySelective dopamine D2/D3 receptor antagonist (Ki values are 0.50 and 0.16 nM respectively). Antipsychotic.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Claytor et al (2006) The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys. Pharmacol.Biochem.Behav. 83 456. PMID: 16631246.
Giuliani and Ferrari (1997) Involvement of dopamine receptors in the antipsychotic profile of (-) eticlopride. Physiol.Behav. 61 563. PMID: 9108576.
Hall et al (1985) Some in vitro receptor binding properties of [3H]eticlopride, a novel substituted benzamide, selective for dopamine-D2 receptors in the rat brain. Eur.J.Pharmacol. 111 191. PMID: 4018125.
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Citations are publications that use Tocris products. Selected citations for Eticlopride hydrochloride include:
Jensen (2015) Effects of Dopamine D2-Like Receptor Antagonists on Light Responses of Ganglion Cells in Wild-Type and P23H Rat Retinas. PLoS One 10 e0146154. PMID: 26717015.
Tønnesen et al (2011) Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model. PLoS One 6 e17560. PMID: 21394212.
Burgess et al (2010) Dopaminergic regulation of sleep and cataplexy in a murine model of narcolepsy. Sleep 33 1295. PMID: 21061851.
Do you know of a great paper that uses Eticlopride hydrochloride from Tocris? If so please let us know.
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Keywords: Eticlopride hydrochloride, supplier, Selective, antagonists, D3, D2, Dopamine, D2-like, Non-Selective, Receptors, dopaminergic, Tocris Bioscience, Non-selective Dopamine Antagonist products
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