BIM 23056

Cat. No. 1844

BIM 23056 D-Phe-Phe-Tyr-D-Trp-Lys-Val-Phe-D-Nal-NH2

Price and Availability

For BIM 23056 pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Biological Activity

Somatostatin receptor ligand (Ki values are 142, > 1000, 10.8, 16.6 and 5.7 nM for human cloned sst1 - 5 receptors respectively). Behaves as an antagonist on SRIF14-induced [35S]-GTPγS binding at sst3 and sst5 receptors (PKB values are 6.33 and 5.84 respectively).

Technical Data

M.Wt:
1232.49
Formula:
C71H81N11O9
Sequence:
FFYWKVFX

(Modifications: Phe-1 = D-Phe, Trp-4 = D-Trp, X = D-Nal & C-terminal amide)

Solubility:
Soluble to 1 mg/ml in 20% acetonitrile / water
Storage:
Desiccate at -20°C
CAS No:
150155-61-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
Select another batch:

References are publications that support the products' biological activity.

Siehler and Hoyer (1999) Characterisation of human recombinant somatostatin receptors. Modulation of GTPgammaS binding. Naunyn Schmiedebergs Arch.Pharmacol. 360 500. PMID: 10598789.

Wilkinson et al (1996) Potent antagonism by BIM-23056 at the human recombinant somatostatin sst5 receptor. Br.J.Pharmacol. 118 445. PMID: 8762063.

Patel and Srikant (1994) Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5). Endocrinology 135 2814. PMID: 7988476.

Raynor et al (1993) Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol.Pharmacol. 43 838. PMID: 8100350.

If you know of a relevant reference for BIM 23056 please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses BIM 23056 from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: BIM 23056, supplier, Somatostatin, receptor, agonists, Receptors, BIM23056, Tocris Bioscience, Somatostatin (sst) Receptor products

Quick Order

Find multiple products by catalog number

divider line

Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors. Request copy or view PDF today.

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

Regulation of Vascular Reactivity by GPCRs

Written by J.J. Maguire and A.P. Davenport

Cardiovascular Life Science Poster

Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity. Request copy or view PDF today.

divider line

New Products in this Area

Retrobradykinin

Reverse analog of Bradykinin

TASP 0390325

Potent and selective V1B receptor antagonist; orally bioavailable

ML 233

Non-peptide apelin receptor agonist

BML 111

FPR2 (lipoxin A4 receptor) agonist

Amylin (rat)

Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors

Calcitonin (human)

Endogenous calcitonin receptor agonist; inhibits bone resorption

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.