(+)-Clopidogrel hydrogen sulfate

Cat. No. 1820

(+)-Clopidogrel hydrogen sulfate C16H16ClNO2S.H2SO4 [120202-66-6]

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Alternative Name: Plavix

Chemical Name: (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogen sulfate

Biological Activity

Selective, high affinity P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity. Active enantiomer of (±)-clopidogrel hydrochloride (Cat. No. 2490).

Technical Data

M.Wt:
419.9
Formula:
C16H16ClNO2S.H2SO4
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
120202-66-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Kugelgen (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 110 415. PMID: 16257449.

Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31 174.

Savi et al (2001) P2Y12, a new platelet ADP receptor, target of clopidogrel. Biochem.Biophys.Res.Comm. 283 379.

Reist et al (2000) Very low chiral inversion of clopidogrel in rats: a pharmacokinetic and mechanistic investigation. Drug Metab.Disp. 28 1405.

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Keywords: (+)-Clopidogrel hydrogen sulfate, supplier, clopidogrel, p2y12, purinergic, receptors, antagonists, inhibits, inhibitors, platelet, aggregation, plavix, antithrombotic, agents, Tocris Bioscience, Purinergic (P2Y) Receptor Antagonist products

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