Cat. No. 1812
Alternative Name: Ritalin
Chemical Name: Threo-methyl α-Phenyl-2-piperidineacetate hydrochloride
Biological ActivityPsychomotor stimulant. Inhibitor of dopamine and noradrenalin transporters that increases the extracellular concentration of dopamine and noradrenalin. Increases locomotor activity in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Askenasy et al (2007) Methylphenidate (Ritalin): behavioral studies in the rat. Int.J.Neurosci. 117 757. PMID: 17454243.
Leonard et al (2004) Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects. Human Psychopharm. 19 151.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for Threo-methylphenidate hydrochloride include:
Parker et al (2014) Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish. PLoS One 231 2671. PMID: 24481568.
Poulin et al (2014) Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics. Mol Pharmacol 86 378. PMID: 25028482.
Do you know of a great paper that uses Threo-methylphenidate hydrochloride from Tocris? If so please let us know.
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Keywords: Threo-methylphenidate hydrochloride, supplier, inhibitors, inhibits, dopamine, DAT, noradrenalin, noradrenaline, NET, adrenalin, transporters, Psychomotor, stimulants, neurotransmitter, Tocris Bioscience, Dopamine Transporter Inhibitor products