Cat. No. 1797

OMDM-2 C27H45NO3 [616884-63-0]

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Chemical Name: (9Z)-N-[1-((R)-4-Hydroxbenzyl)-2-hydroxyethyl]-9-octadecenamide

Biological Activity

Metabolically stable inhibitor of anandamide cellular uptake (Ki = 3 μM). Displays relatively low affinity for CB1 and CB2 receptors (Ki values are 5.1 and > 10 μM) and for vanilloid VR1 receptors (EC50 = 10 μM). Has minimal activity against FAAH (Ki > 50 μM). Active in vivo.

Technical Data

Soluble to 10 mM in ethanol and to 10 mM in DMSO
>99 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

de Lago et al (2004) In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake. Eur.J.Pharmacol. 484 249. PMID: 14744610.

Ortar et al (2003) Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem.Pharmacol. 35 1473. PMID: 12732359.

If you know of a relevant reference for OMDM-2 please let us know.

Citations are publications that use Tocris products. Selected citations for OMDM-2 include:

Bátkai et al (2004) Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. FASEB J 110 1996. PMID: 15451779.

Do you know of a great paper that uses OMDM-2 from Tocris? If so please let us know.

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Keywords: OMDM-2, supplier, Potent, inhibitors, inhibits, anandamide, reuptake, AMT, Transporters, cannabinoids, Monoamine, Neurotransmitter, Tocris Bioscience, Cannabinoid Transporter Inhibitor products

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