JWH 133 (in Tocrisolve™ 100)
Cat. No. 1783
Chemical Name: (6aR,10aR)-3-(1,1-dimethylbutyl)-6a
Biological ActivityPotent CB2 selective agonist (Ki = 3.4 nM), in water-soluble emulsion (for details see TocrisolveTM 100 Cat. No. 1684). Approx. 200-fold selective over CB1 receptors. Active in vivo, reducing spasticity in a murine model of multiple sclerosis. JWH 133 also available as a solid (Cat. No. 1343).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Baker et al (2000) Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 404 84. PMID: 10716447.
Huffman et al (1999) 3-(1'-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorg.Med.Chem. 7 2905. PMID: 10658595.
Pertwee (1999) Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 6 635. PMID: 10469884.
If you know of a relevant reference for JWH 133 (in Tocrisolve™ 100) please let us know.
Citations are publications that use Tocris products. Selected citations for JWH 133 (in Tocrisolve™ 100) include:
Williams et al (2014) △(9)-Tetrahydrocannabinol treatment during human monocyte differentiation reduces macrophage susceptibility to HIV-1 infection. Autophagy 9 369. PMID: 24562630.
Do you know of a great paper that uses JWH 133 (in Tocrisolve™ 100) from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: JWH 133 (in Tocrisolve 100), supplier, Potent, selective, CB2, agonists, water-soluble, emulsion, cannabinoids, Receptors, JWH133, cb2r, Tocris Bioscience, CB2 Receptor Agonist products