Cat. No. 1765
Alternative Name: 3-CBW
Chemical Name: (αS)-α-Amino-3-[(4-carboxyphenyl)meth
Biological ActivityAMPA and kainate receptor antagonist. Inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
More et al (2003) Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br.J.Pharmacol. 138 1093. PMID: 12684265.
More et al (2002) The novel antagonist 3-CBW discriminates between kainate receptors expressed on neonatal rat motoneurones and those on dorsal root C-fibres. Br.J.Pharmacol. 137 1125. PMID: 12429586.
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Keywords: UBP 282, supplier, AMPA/kainate, antagonists, receptors, Glutamate, AMPA, iGluR, Ionotropic, Kainate, UBP282, 3CBW, Tocris Bioscience, AMPA Receptor Antagonist products
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