DOB hydrochloride

Cat. No. 2863

DOB hydrochloride C11H16BrNO2.HCl [29705-96-2]

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Alternative Name: 2,5-Dimethoxy-4-bromoamphetamine hydrochloride

Chemical Name: 4-Bromo-2,5-dimethoxy-α-methylbenzeneethanamine hydrochloride

Biological Activity

Selective 5-HT2 receptor agonist (Ki values are 0.44, 59, 69, 831 and 3700 nM for 5-HT2H, 5-HT2L, 5-HT2C, 5-HT1B and 5-HT1A receptors respectively). Hallucinogenic.

Technical Data

M.Wt:
310.62
Formula:
C11H16BrNO2.HCl
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
29705-96-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Arvanov et al (1999) A pre- and postsynaptic modulatory action of 5-HT and the 5-HT2A,2C receptor agonist DOB on NMDA-evoked responses in the rat medial prefrontal cortex. Eur.J.Neurosci. 11 2917. PMID: 10457188.

McKenna et al (1989) Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin. J.Neurosci. 10 3482.

Titiler et al (1987) Selectivity of serotonergic drugs for multiple brain serotonin receptors. Biochem.Pharmacol. 36 3265. PMID: 3663239.

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Keywords: DOB hydrochloride, supplier, Selective, 5-HT2, agonists, Non-Selective, Serotonin, Receptors, Tocris Bioscience, Non-selective 5-HT2 Agonist products

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