Cat. No. 2863
Alternative Name: 2,5-Dimethoxy-4-bromoamphetamine hydrochloride
Chemical Name: 4-Bromo-2,5-dimethoxy-α-methylbenzen
Biological ActivitySelective 5-HT2 receptor agonist (Ki values are 0.44, 59, 69, 831 and 3700 nM for 5-HT2H, 5-HT2L, 5-HT2C, 5-HT1B and 5-HT1A receptors respectively). Hallucinogenic.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Arvanov et al (1999) A pre- and postsynaptic modulatory action of 5-HT and the 5-HT2A,2C receptor agonist DOB on NMDA-evoked responses in the rat medial prefrontal cortex. Eur.J.Neurosci. 11 2917. PMID: 10457188.
McKenna et al (1989) Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin. J.Neurosci. 10 3482.
Titiler et al (1987) Selectivity of serotonergic drugs for multiple brain serotonin receptors. Biochem.Pharmacol. 36 3265. PMID: 3663239.
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Citations are publications that use Tocris products.
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Keywords: DOB hydrochloride, supplier, Selective, 5-HT2, agonists, Non-Selective, Serotonin, Receptors, Tocris Bioscience, Non-selective 5-HT2 Agonist products