Risperidone

Cat. No. 2865

Risperidone C23H27FN4O2 [106266-06-2]

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Alternative Name: R 64 766

Chemical Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Biological Activity

Atypical antipsychotic agent that displays 5-HT2A receptor antagonism. Also displays high affinity at D2 receptors (Ki values are 0.4 and 3.13 nM for 5-HT2A and D2 receptors respectively).

Technical Data

M.Wt:
410.48
Formula:
C23H27FN4O2
Solubility:
Soluble to 10 mM in DMSO and to 10 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
106266-06-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Stathis et al (1996) Risperidone: a novel antipsychotic with many "atypical" properties. Psychopharmacol. 127 181.

Leysen et al (1994) Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity. J.Clin.Psychiatry 55 (Suppl.) 5. PMID: 7520908.

Leysen et al (1988) Biochemical profile of risperidone, a new antipsychotic. J.Pharmacol.Exp.Ther. 247 661. PMID: 2460616.

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Keywords: Risperidone, supplier, 5-HT2A, antagonists, D2, Serotonin, Receptors, Dopamine, dopaminergic, R64766, Tocris Bioscience, 5-HT2A Receptor Antagonist products

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