Cat. No. 2865
Alternative Name: R 64 766
Chemical Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-
Biological ActivityAtypical antipsychotic agent that displays 5-HT2A receptor antagonism. Also displays high affinity at D2 receptors (Ki values are 0.4 and 3.13 nM for 5-HT2A and D2 receptors respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Stathis et al (1996) Risperidone: a novel antipsychotic with many "atypical" properties. Psychopharmacol. 127 181.
Leysen et al (1994) Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity. J.Clin.Psychiatry 55 (Suppl.) 5. PMID: 7520908.
Leysen et al (1988) Biochemical profile of risperidone, a new antipsychotic. J.Pharmacol.Exp.Ther. 247 661. PMID: 2460616.
If you know of a relevant reference for Risperidone please let us know.
Citations are publications that use Tocris products. Selected citations for Risperidone include:
Canfrán-Duque et al (2015) Curcumin Mitigates the Intracellular Lipid Deposit Induced by Antipsychotics In Vitro. Sci Rep 10 e0141829. PMID: 26517556.
Do you know of a great paper that uses Risperidone from Tocris? If so please let us know.
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Keywords: Risperidone, supplier, 5-HT2A, antagonists, D2, Serotonin, Receptors, Dopamine, dopaminergic, R64766, Tocris Bioscience, 5-HT2A Receptor Antagonist products