Ionomycin calcium salt

Cat. No. 1704

Ionomycin calcium salt C41H70O9.Ca [56092-82-1]

Price and Availability

For Ionomycin calcium salt pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid calcium salt

Biological Activity

Calcium ionophore; more specific than A23187 (Cat. No. 1234).

Technical Data

M.Wt:
747.08
Formula:
C41H70O9.Ca
Solubility:
Soluble to 100 mM in ethanol and to 25 mM in DMSO with gentle warming
Purity:
>98 %
Storage:
Desiccate at -20°C
CAS No:
56092-82-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
Select another batch:

Elzi et al (2001) Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. Am.J.Physiol.Cell Physiol. 281 C350. PMID: 11401859.

Kaufmann et al (1980) Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria. J.Biol.Chem. 255 2735. PMID: 6766939.

Liu and Hermann (1978) Characterization of ionomycin as a calcium ionophore. J.Biol.Chem. 253 5892. PMID: 28319.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Ionomycin calcium salt include:

Azab et al (2015) Binding of αherpesvirus Glycoprotein H to Surface α4β1-Integrins Activates Calcium-Signaling Pathways and Induces Phosphatidylserine Exposure on the Plasma Membrane. PLoS One 6. PMID: 26489864.

Jonas et al (2015) Assessment of TTX-s and TTX-r Action Potential Conduction along Neurites of NGF and GDNF Cultured Porcine DRG Somata. J Pharmacol Exp Ther 10 e0139107. PMID: 26407014.

Plog et al (2015) Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype. PLoS One 10 e0140050. PMID: 26474299.

Shambharkar et al (2015) TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis. MBio 10 e0127480. PMID: 25996873.

Barcomb et al (2013) Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B. Mol Pharmacol 84 834. PMID: 24056996.

Soltoff and Lannon (2013) Activation of ERK1/2 by store-operated calcium entry in rat parotid acinar cells. PLoS One 8 e72881. PMID: 24009711.

Selway et al (2012) Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1. PLoS One 7 e33004. PMID: 22412973.

Ohya et al (2011) Involvement of dominant-negative spliced variants of the intermediate conductance Ca2+-activated K+ channel, K(Ca)3.1, in immune function of lymphoid cells. J Biol Chem 286 16940. PMID: 21345794.

Do you know of a great paper that uses Ionomycin calcium salt from Tocris? If so please let us know.show all ▼show less ▲

View Related Products by Product Action

Keywords: Ionomycin calcium salt, supplier, Calcium, ionophore, Ca2+, Ionophore, Signaling, Signalling, Agents, General, antibiotics, Tocris Bioscience, General Calcium Signaling Agent products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

New Product Guide (Fall/Winter 2016)

Our New Product guide highlights over 100 new products added in the second half of 2016. Request copy or view PDF today.

divider line

Bio-Techne Events

One Day Symposium

Bio-Techne Symposium 2017

Epigenetic Regulation of Stem Cell Differentiation

March 1, 2017

Amsterdam, The Netherlands