Cilostazol

Cat. No. 1692

Cilostazol C20H27N5O2 [73963-72-1]

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Chemical Name: 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone

Biological Activity

Potent phosphodiesterase III A (PDE3A) inhibitor (IC50 = 0.2 μM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.

Technical Data

M.Wt:
369.47
Formula:
C20H27N5O2
Solubility:
Soluble to 10 mM in ethanol and to 50 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
73963-72-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Schror (2002) The pharmacology of cilostazol. Diabetes Obes.Metab. 4 S14. PMID: 12180353.

Shintani et al (1985) General pharmacological properties of cilostazol, a new antithrombotic drug. Part I: effects on the central nervous system. Arzneimittelforschung 35 1157. PMID: 4074429.

Shintani et al (1985) General pharmacological properties of cilostazol, a new antithrombotic drug. Part II: effects on the peripheral organs. Arzneimittelforschung 35 1163. PMID: 3000392.

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Keywords: Cilostazol, supplier, PDE3A, inhibitors, inhibits, adenosines, reuptake, Phosphodiesterases, ENT1, Purine, Transporters, Pyrimidine, Equilibrative, Nucleoside, Monoamine, Neurotransmitter, Tocris Bioscience, Phosphodiesterase Inhibitor products

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