Cat. No. 1641

OLDA C26H43NO3 [105955-11-1]

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Alternative Name: N-Oleoyldopamine

Chemical Name: (9Z)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-9-octadecenamide

Biological Activity

Potent endogenous vanilloid TRPV1 (VR1) receptor agonist (EC50 = 36 nM at hVR1) with low affinity for rCB1 receptors (Ki = 1.6 μM). Potently induces VR1-mediated thermal hyperalgesia in rats in vivo.

Technical Data

Soluble to 50 mM in DMSO and to 50 mM in ethanol
>99 %
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Butelman et al (2004) Anitallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates. J.Pharmacol.Exp.Ther. 311 155. PMID: 15152028.

Chu et al (2003) N-Oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J.Biol.Chem. 278 13633. PMID: 12569099.

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Citations are publications that use Tocris products.

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Keywords: OLDA, supplier, Potent, selective, endogenous, TRPV1, agonists, Vanillioid, Receptors, VR1, TRPV, Channels, Transient, Receptor, Potential, Tocris Bioscience, TRPV Agonist products

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